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R语言的multi_cox.r怎么用

发表于:2025-11-17 作者:千家信息网编辑
千家信息网最后更新 2025年11月17日,本篇内容主要讲解"R语言的multi_cox.r怎么用",感兴趣的朋友不妨来看看。本文介绍的方法操作简单快捷,实用性强。下面就让小编来带大家学习"R语言的multi_cox.r怎么用"吧!multi_
千家信息网最后更新 2025年11月17日R语言的multi_cox.r怎么用

本篇内容主要讲解"R语言的multi_cox.r怎么用",感兴趣的朋友不妨来看看。本文介绍的方法操作简单快捷,实用性强。下面就让小编来带大家学习"R语言的multi_cox.r怎么用"吧!

multi_cox.r 多因素cox分析

使用方法:

指定多个基因表达量做多因素cox回归分析,并构建预后模型,以及评估预后模型:

$Rscript $scriptdir/multi_cox.r -husage: /share/nas1/huangls/test/TCGA_immu/scripts/multi_cox.r       [-h] -i data -t time -e event -v variate [variate ...]       [-P predict.time [predict.time ...]] [-c cut.score] [-s seed]       [-o outdir] [-p prefix]multi variate cox regression analysis using gene expressionoptional arguments:  -h, --help            show this help message and exit  -i data, --data data  input data file path[required]  -t time, --time time  set suvival time column name [required]  -e event, --event event                        set event column name must 0 or 1 code format                        [required]  -v variate [variate ...], --variate variate [variate ...]                        variate for cox analysis [required]  -P predict.time [predict.time ...], --predict.time predict.time [predict.time ...]                        Time point to draw the ROC curve [default 365 1095                        1825]  -c cut.score, --cut.score cut.score                        set cut score value to divide high and low risk groups                        [default median]  -s seed, --seed seed  set random seed [default 2021]  -o outdir, --outdir outdir                        output file directory [default cwd]  -p prefix, --prefix prefix                        out file name prefix [default cox]

使用举例:

Rscript $scriptdir/multi_cox.r -i imm.unicox.metadata-exp.tsv -e EVENT -t TIME \    -v PDGFRL CXCR4 PAK3 CSF1R PDCD1 -P  365 1095 1825 \    -o multicox   -p  multicox

参数说明:

-i 输入生存数据与基因表达文件

barcodeTIMEEVENTFGRCD38ITGALCX3CL1CEACAM21MATKCD79BMMP25
TCGA-B7-A5TK-01A-12R-A36D-31288016.3440886.8677240.26903603.01321.8685362.283423.45319813.72829
TCGA-BR-7959-01A-11R-2343-131010011.9673915.794517.35856626.913532.5719170.8641161.8799573.451148
TCGA-IN-8462-01A-11R-2343-1357205.3508463.1113423.76912520.222380.6108390.5197762.8221921.106563
TCGA-CG-4443-01A-01R-1157-1391201.538020.8629552.3735119.040971.0921270.7603481.9265920.878735
TCGA-KB-A93J-01A-11R-A39E-311124015.2401613.304738.0859114.152953.4835593.1929513.65174210.43186
TCGA-HU-A4H3-01A-21R-A251-3188206.2617612.6751737.0258864.0502710.5841591.0393361.9792142.312993
TCGA-RD-A8MV-01A-11R-A36D-313720027.0741520.1588534.9130934.718214.1131122.61555716.5194617.72674
TCGA-VQ-A91X-01A-12R-A414-3128911.0623410.7520182.3805134.4158150.5181420.2121971.2392030.582114











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